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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLR9
All Species:
13.03
Human Site:
S991
Identified Species:
47.78
UniProt:
Q9NR96
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR96
NP_059138.1
1032
115860
S991
R
Q
R
L
C
R
Q
S
V
L
L
W
P
H
Q
Chimpanzee
Pan troglodytes
XP_001171340
1325
149159
S1284
R
Q
R
L
C
R
Q
S
V
L
L
W
P
H
Q
Rhesus Macaque
Macaca mulatta
NP_001123903
1032
115711
S991
R
Q
R
L
C
R
Q
S
V
L
L
W
P
H
Q
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQU3
1032
116330
S991
R
Q
R
L
C
R
Q
S
V
L
F
W
P
Q
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506154
1013
112781
V972
L
D
D
K
Q
D
V
V
V
L
V
I
L
G
Q
Chicken
Gallus gallus
Q9DGB6
781
89077
A741
L
E
P
I
Q
S
Q
A
I
P
K
R
F
C
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001124066
1057
121075
K1016
Q
M
R
K
R
L
C
K
K
S
V
L
S
W
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.2
95.8
N.A.
N.A.
75.6
N.A.
N.A.
57.4
23.6
N.A.
38.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
77.5
97.2
N.A.
N.A.
83.5
N.A.
N.A.
68.3
38.8
N.A.
55
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
N.A.
N.A.
20
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
86.6
N.A.
N.A.
26.6
40
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
58
0
15
0
0
0
0
0
0
15
0
% C
% Asp:
0
15
15
0
0
15
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
15
0
15
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
43
0
% H
% Ile:
0
0
0
15
0
0
0
0
15
0
0
15
0
0
0
% I
% Lys:
0
0
0
29
0
0
0
15
15
0
15
0
0
0
15
% K
% Leu:
29
0
0
58
0
15
0
0
0
72
43
15
15
0
0
% L
% Met:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
15
0
0
0
0
0
0
15
0
0
58
0
15
% P
% Gln:
15
58
0
0
29
0
72
0
0
0
0
0
0
15
72
% Q
% Arg:
58
0
72
0
15
58
0
0
0
0
0
15
0
0
0
% R
% Ser:
0
0
0
0
0
15
0
58
0
15
0
0
15
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
15
15
72
0
29
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
58
0
15
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _